Good Cosmetic Ingredient NOAEL Data

Coriandrum Sativum Oil (Seed Oil)

INCI: CORIANDRUM SATIVUM OIL

CAS Number
8008-52-4
Function
Fragrance, skin conditioning, masking
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS (21 CFR 182.20); FDA-listed as Substances Added to Food

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Coriandrum Sativum Oil (Seed Oil). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 6000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 160 mg/kg bw/day oral rat oral REACH
NOAEL 600 mg/kg bw/day oral rat oral REACH
NOAEL 500 mg/kg bw/day oral mouse oral REACH
NOAEL 100 mg/kg bw/day oral dog oral REACH
NOAEL 500 mg/kg bw/day oral rat oral REACH
NOAEL 160 mg/kg bw/day oral rat oral REACH
NOAEL 160 mg/kg bw/day oral - oral REACH
NOAEL 250 mg/kg bw/day dermal rat dermal REACH
NOAEL >=532.1 mg/kg bw/day oral rat oral REACH

Expert Verdict

CLP classification shows skin sensitizer and eye damage hazards in neat form; linalool content (~70%) requires EU fragrance allergen labelling; irritating to rabbits but safe at in-use concentrations; IFRA compliance required.

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Concern Level: Moderate

Regulatory Flags

plant-oil potential-allergen fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Coriandrum Sativum Oil (Seed Oil) safe in cosmetics?

CLP classification shows skin sensitizer and eye damage hazards in neat form; linalool content (~70%) requires EU fragrance allergen labelling; irritating to rabbits but safe at in-use concentrations; IFRA compliance required. The EU classifies Coriandrum Sativum Oil (Seed Oil) as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Coriandrum Sativum Oil (Seed Oil) allowed in the EU?

Coriandrum Sativum Oil (Seed Oil) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Coriandrum Sativum Oil (Seed Oil) do in cosmetics?

Coriandrum Sativum Oil (Seed Oil) functions as: Fragrance, skin conditioning, masking. It is classified as a cosmetic ingredient in our database. CAS number: 8008-52-4.

What is the Margin of Safety for Coriandrum Sativum Oil (Seed Oil)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Coriandrum Sativum Oil (Seed Oil)?

The NOAEL (No Observed Adverse Effect Level) for Coriandrum Sativum Oil (Seed Oil) is 6000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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