Crocus Sativus Flower Extract

INCI: CROCUS SATIVUS FLOWER EXTRACT

CAS Number
84604-17-1
Function
Antioxidant, Skin Conditioning, Skin Protecting, Smoothing, Soothing, Moisturising
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA monograph or OTC classification. Not listed as a color additive for cosmetic use. No specific restrictions under US cosmetic ingredient provisions. No CIR safety review completed.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Crocus Sativus Flower Extract (CAS 84604-17-1, EINECS 283-295-0) is permitted in the EU with no restrictions and not listed in any annex. FDA has no monograph or specific restrictions. Non-mutagenic with oral LD50 of 4,120 mg/kg in mice. Typical cosmetic use 0.001%-0.5%. Functions as antioxidant and skin conditioner; sensitization documented primarily in occupational settings and atopic populations, not typical end-use concentrations.

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Concern Level: Low

Regulatory Flags

no-sccs-opinion no-cir-review no-dermal-absorption-data occupational-sensitizer atopic-sensitization-risk no-mos-calculated leave-on-caution safety-assessor-required ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Crocus Sativus Flower Extract safe in cosmetics?

Crocus Sativus Flower Extract (CAS 84604-17-1, EINECS 283-295-0) is permitted in the EU with no restrictions and not listed in any annex. FDA has no monograph or specific restrictions. Non-mutagenic with oral LD50 of 4,120 mg/kg in mice. Typical cosmetic use 0.001%-0.5%. Functions as antioxidant and skin conditioner; sensitization documented primarily in occupational settings and atopic populations, not typical end-use concentrations. The EU classifies Crocus Sativus Flower Extract as "permitted". Safety rating: GOOD.

Is Crocus Sativus Flower Extract allowed in the EU?

Crocus Sativus Flower Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Crocus Sativus Flower Extract do in cosmetics?

Crocus Sativus Flower Extract functions as: Antioxidant, Skin Conditioning, Skin Protecting, Smoothing, Soothing, Moisturising. It is classified as a cosmetic ingredient in our database. CAS number: 84604-17-1.

What is the Margin of Safety for Crocus Sativus Flower Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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