Excellent Cosmetic Ingredient NOAEL Data GHS Classified

Zea Mays Starch

INCI: ZEA MAYS STARCH

CAS Number
9005-25-8
Function
Abrasive, Absorbent, Skin Protectant, Viscosity Increasing, Film-Forming
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA OTC Monograph GRAS at 10-98% as skin protectant. GRAS for food.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Zea Mays Starch. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 77000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
dose_tested 77000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.

Expert Verdict

Safe per CIR 2011 for use 0.00002%-99%. No acute toxicity, slight transient eye irritation. FDA recognizes as drug active (skin protectant) when labeled with drug claims.

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Concern Level: None

Regulatory Flags

eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Zea Mays Starch safe in cosmetics?

Safe per CIR 2011 for use 0.00002%-99%. No acute toxicity, slight transient eye irritation. FDA recognizes as drug active (skin protectant) when labeled with drug claims. The EU classifies Zea Mays Starch as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.

Is Zea Mays Starch allowed in the EU?

Zea Mays Starch EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Zea Mays Starch do in cosmetics?

Zea Mays Starch functions as: Abrasive, Absorbent, Skin Protectant, Viscosity Increasing, Film-Forming. It is classified as a cosmetic ingredient in our database. CAS number: 9005-25-8.

What is the Margin of Safety for Zea Mays Starch?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Zea Mays Starch?

The NOAEL (No Observed Adverse Effect Level) for Zea Mays Starch is 77000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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