Excellent Cosmetic Ingredient NOAEL Data GHS Classified

Ricinus Communis Seed Oil

INCI: RICINUS COMMUNIS SEED OIL

CAS Number
8001-79-4
Function
Emollient, Skin Conditioning
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Ricinus Communis Seed Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3045 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 7823 mg/kg bw/day oral mouse Subchronic COSMOS_DB
NOAEL 12840 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 12840 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 11329 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB
NOAEL 10 other oral rat oral REACH
NOAEL 10 other oral mouse oral REACH
NOAEL >=15 other oral rat oral REACH
NOAEL 200000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the gastrointestinal tract.
Long-term Exposure Effects
Repeated or prolonged contact with skin may cause dermatitis.

Expert Verdict

CIR (2007, reaffirmed Dec 2024) concluded safe. Not a significant irritant or sensitizer in standard populations; rare allergic contact dermatitis in lip products. Castor oil does not contain ricin.

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Concern Level: Low

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Ricinus Communis Seed Oil safe in cosmetics?

CIR (2007, reaffirmed Dec 2024) concluded safe. Not a significant irritant or sensitizer in standard populations; rare allergic contact dermatitis in lip products. Castor oil does not contain ricin. The EU classifies Ricinus Communis Seed Oil as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.

Is Ricinus Communis Seed Oil allowed in the EU?

Ricinus Communis Seed Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ricinus Communis Seed Oil do in cosmetics?

Ricinus Communis Seed Oil functions as: Emollient, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 8001-79-4.

What is the Margin of Safety for Ricinus Communis Seed Oil?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ricinus Communis Seed Oil?

The NOAEL (No Observed Adverse Effect Level) for Ricinus Communis Seed Oil is 3045 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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