D-Phenylalanyl Tripeptide-75

INCI: D-PHENYLALANYL TRIPEPTIDE-75

CAS Number
Not found in public cosmetic ingredient lists; CAS likely provided by supplier or patent documentation for specific sequence
Function
Anti-ageing and dermal-restructuring peptide; tripeptides stimulate synthesis of collagen I/IV, elastin, and other extracellular matrix components, improving firmness, elasticity, and stretch-mark appearance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted; considered a cosmetic ingredient provided claims remain cosmetic (appearance of wrinkles, firmness) and safety is substantiated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited transparent toxicology data available; mechanistic stimulation of extracellular matrix should be assessed for potential fibrosis-like or unwanted proliferative effects in long-term high-dose scenarios; supplier dossier review is critical

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Concern Level: Moderate

Frequently Asked Questions

Is D-Phenylalanyl Tripeptide-75 safe in cosmetics?

Limited transparent toxicology data available; mechanistic stimulation of extracellular matrix should be assessed for potential fibrosis-like or unwanted proliferative effects in long-term high-dose scenarios; supplier dossier review is critical The EU classifies D-Phenylalanyl Tripeptide-75 as "permitted". Safety rating: GOOD.

Is D-Phenylalanyl Tripeptide-75 allowed in the EU?

D-Phenylalanyl Tripeptide-75 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does D-Phenylalanyl Tripeptide-75 do in cosmetics?

D-Phenylalanyl Tripeptide-75 functions as: Anti-ageing and dermal-restructuring peptide; tripeptides stimulate synthesis of collagen I/IV, elastin, and other extracellular matrix components, improving firmness, elasticity, and stretch-mark appearance. It is classified as a cosmetic ingredient in our database. CAS number: Not found in public cosmetic ingredient lists; CAS likely provided by supplier or patent documentation for specific sequence.

What is the Margin of Safety for D-Phenylalanyl Tripeptide-75?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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