MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP)
INCI: NOT A RECOGNIZED COSMETIC INCI NAME - THIS IS AN INDUSTRIAL CHEMICAL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 150 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1.07 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 0.357 mg/kg bw/day | dermal | code:3543 | dermal | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Extremely hazardous. Strong oxidizer; causes severe skin burns and serious eye damage. Corrosive to tissues; organic peroxide oxygen generates free radicals that damage cellular metabolism. Explosive when concentrated or heated. No safe cosmetic application exists.. Colorless liquid; thermally unstable; must be stored with phlegmatizer (dimethyl phthalate); classified as Organic Peroxide Type D under GHS. Inclusion here appears to be a database artifact from the "MEK" name proximity - this is...
Frequently Asked Questions
Is MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) safe in cosmetics?
Extremely hazardous. Strong oxidizer; causes severe skin burns and serious eye damage. Corrosive to tissues; organic peroxide oxygen generates free radicals that damage cellular metabolism. Explosive when concentrated or heated. No safe cosmetic application exists.. Colorless liquid; thermally unstable; must be stored with phlegmatizer (dimethyl phthalate); classified as Organic Peroxide Type D under GHS. Inclusion here appears to be a database artifact from the "MEK" name proximity - this is... The EU classifies MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) as "permitted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) allowed in the EU?
MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) do in cosmetics?
MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) functions as: Oxidizing agent / catalyst (industrial use: initiator for room-temperature curing of unsaturated polyester resins). It is classified as a cosmetic ingredient in our database. CAS number: 1338-23-4.
What is the Margin of Safety for MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP)?
The NOAEL (No Observed Adverse Effect Level) for MEK Peroxides (Methyl Ethyl Ketone Peroxide / MEKP) is 150 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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