Decafluoropentane

INCI: DECAFLUOROPENTANE

CAS Number
138495‑42‑8.
Function
Solvent and propellant-type volatile used in specialty formulations; falls under per- and polyfluoroalkyl substances (PFAS) class.
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Identified in FDA's mandated report on PFAS in cosmetics; FDA notes significant data gaps on PFAS dermal absorption and toxicity and is continuing to assess safety; no PFAS-specific cosmetic ban yet at federal level, but MoCRA requires ongoing review.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

PFAS class ingredient with persistence, bioaccumulation potential, and systemic effect concerns; regulatory scrutiny ongoing; reputational risk and future ban potential warrant avoidance in clean or eco-positioned lines.

⚠️
Concern Level: High

Frequently Asked Questions

Is Decafluoropentane safe in cosmetics?

PFAS class ingredient with persistence, bioaccumulation potential, and systemic effect concerns; regulatory scrutiny ongoing; reputational risk and future ban potential warrant avoidance in clean or eco-positioned lines. The EU classifies Decafluoropentane as "prohibited". Safety rating: MODERATE.

Is Decafluoropentane allowed in the EU?

Decafluoropentane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Decafluoropentane do in cosmetics?

Decafluoropentane functions as: Solvent and propellant-type volatile used in specialty formulations; falls under per- and polyfluoroalkyl substances (PFAS) class.. It is classified as a cosmetic ingredient in our database. CAS number: 138495‑42‑8..

What is the Margin of Safety for Decafluoropentane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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