Decapeptide-5

INCI: DECAPEPTIDE-5

CAS Number
Not assigned in CosIng; request from supplier
Function
Skin conditioning, skin protecting (signaling peptide)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; general cosmetic safety under 21 CFR 740.10

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data gap: no published repeated-dose tox, geno-tox, or reproductive tox studies; supplier dossier mandatory for CPSR

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Concern Level: Low

Frequently Asked Questions

Is Decapeptide-5 safe in cosmetics?

Data gap: no published repeated-dose tox, geno-tox, or reproductive tox studies; supplier dossier mandatory for CPSR The EU classifies Decapeptide-5 as "permitted". Safety rating: GOOD.

Is Decapeptide-5 allowed in the EU?

Decapeptide-5 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Decapeptide-5 do in cosmetics?

Decapeptide-5 functions as: Skin conditioning, skin protecting (signaling peptide). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng; request from supplier.

What is the Margin of Safety for Decapeptide-5?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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