Good Cosmetic Ingredient NOAEL Data SCCS/CIR Reviewed

DI-T-BUTYLHYDROQUINONE

CAS Number
88-58-4
Function
Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

1 study endpoint found for DI-T-BUTYLHYDROQUINONE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 50 mg/kg bw/day oral rat oral REACH

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir Philadelphia 0 1996
Verdict: unknown

Expert Verdict

DI-T-BUTYLHYDROQUINONE is listed in the EU CosIng database with functions: Antioxidant It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted antioxidant needs-enrichment

Frequently Asked Questions

Is DI-T-BUTYLHYDROQUINONE safe in cosmetics?

DI-T-BUTYLHYDROQUINONE is listed in the EU CosIng database with functions: Antioxidant It is permitted in the EU without specific restrictions. The EU classifies DI-T-BUTYLHYDROQUINONE as "Permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is DI-T-BUTYLHYDROQUINONE allowed in the EU?

DI-T-BUTYLHYDROQUINONE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does DI-T-BUTYLHYDROQUINONE do in cosmetics?

DI-T-BUTYLHYDROQUINONE functions as: Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 88-58-4.

What is the NOAEL for DI-T-BUTYLHYDROQUINONE?

The NOAEL (No Observed Adverse Effect Level) for DI-T-BUTYLHYDROQUINONE is 50 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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