Is Dextran Sulfate safe in cosmetics?
Dextran Sulfate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Dextran Sulfate
Also known as: Dextran, hydrogen sulfate, Dextran sulfuric acid, Dextran polysulfate, Polydextran sulfate, Dextran sulfate 500 (+13 more)
INCI: DEXTRAN SULFATE
Dextran Sulfate (CAS 9042-14-2) is a cosmetic cosmetic ingredient functioning as Skin Conditioning, Binding, Film Forming, Viscosity Controlling. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Function
Skin Conditioning, Binding, Film Forming, Viscosity Controlling
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA cosmetic restrictions. Listed in FDA GSRS with multiple MW variants. CIR group assessment (2012) concluded safe at reported use concentrations of 0.005%-0.5%.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Dextran Sulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Binder
Softener and conditioner
Editorial summary
Preliminary editorial summary for Dextran Sulfate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cir-safe
no-sccs-opinion
no-eu-max
no-mos-calculated
data-gap-absorption
mw-dependent-behavior
Known Synonyms
Dextran, hydrogen sulfate
Dextran sulfuric acid
Dextran polysulfate
Polydextran sulfate
Dextran sulfate 500
Dextran sulphate
Dextran sulfate 5000
Sulfopolyglucin
UNII-AIW09WL51K
Dextran sulfuric acid ester
PF 51
MDS-Kowa
T 500
NSC 620255
PF 51 (carbohydrate)
Polyglucin, sulfate
DS 5000
NM 3014
Chemical Function
Softener and conditioner
Binder
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Dextran Sulfate allowed in the EU?
Dextran Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dextran Sulfate do in cosmetics?
Dextran Sulfate functions as: Skin Conditioning, Binding, Film Forming, Viscosity Controlling. It is classified as a cosmetic ingredient in our database. CAS number: 9042-14-2.
Compliance Tools
Check Dextran Sulfate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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