Is Diaminopyrimidine Oxide safe in cosmetics?
Diaminopyrimidine Oxide has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Good
Cosmetic Ingredient
Diaminopyrimidine Oxide
Also known as: 6-Amino-2-iminopyrimidin-1(2H)-ol, 2,4-Pyrimidinediamine, 3-oxide, 2,4-Diaminopyrimidine 3-N-oxide, 2,6-Diaminopyrimidin-1-ium-1-olate
INCI: DIAMINOPYRIMIDINE OXIDE
Diaminopyrimidine Oxide (CAS 74638-76-9) is a cosmetic cosmetic ingredient functioning as Hair Conditioning, Skin Conditioning. EU Regulation 1223/2009 status: restricted, max 1.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 74638-76-9 →
Auto-generated CPSR Part A draft with source citations
Function
Hair Conditioning, Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-hydroxy-2-iminopyrimidin-4-amine
InChIKey
YTKGAYFHUZTLCI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
1.5%
US US Status
permitted
US Notes
Not classified as OTC drug or sunscreen active; used as cosmetic ingredient in the US when marketed for hair conditioning rather than therapeutic regrowth claims.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diaminopyrimidine Oxide.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: Hair products. Max: 0.015.
BRIN Brazil/India Cosmetics
Brazil: Restricted · max 1,5%
India: Restricted · max 0.015
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | restricted | 1.5% | Hair care products (anti-hair loss) |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Regulatory List Membership (1)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Diaminopyrimidine Oxide.
Regulatory Flags
eu-annex-iii
restricted-1.5-percent
sccnfp-approved
no-cir-report
aminexil-kopexil
not-minoxidil-derivative
eu_cosing_listed
Known Synonyms
6-Amino-2-iminopyrimidin-1(2H)-ol
2,4-Pyrimidinediamine, 3-oxide
2,4-Diaminopyrimidine 3-N-oxide
2,6-Diaminopyrimidin-1-ium-1-olate
Chemical Function
Softener and conditioner
Regulatory Lists
Europe; Personal care; restricted
Frequently Asked Questions
Is Diaminopyrimidine Oxide allowed in the EU?
Diaminopyrimidine Oxide EU regulatory status: restricted. Maximum allowed concentration: 1.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Diaminopyrimidine Oxide do in cosmetics?
Diaminopyrimidine Oxide functions as: Hair Conditioning, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 74638-76-9.
Is Diaminopyrimidine Oxide used outside cosmetics?
Diaminopyrimidine Oxide also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Diaminopyrimidine Oxide compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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