Is Aminexil safe in cosmetics?
Aminexil has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted.
Good
Active Ingredient
Aminexil
Also known as: 6-Amino-2-iminopyrimidin-1(2H)-ol, 2,4-Pyrimidinediamine, 3-oxide, 2,4-Diaminopyrimidine 3-N-oxide, 2,6-Diaminopyrimidin-1-ium-1-olate
INCI: DIAMINOPYRIMIDINE OXIDE
Aminexil (CAS 74638-76-9) is a cosmetic active ingredient functioning as Hair conditioning. EU Regulation 1223/2009 status: restricted, max 1.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 74638-76-9 →
Auto-generated CPSR Part A draft with source citations
Function
Hair conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-hydroxy-2-iminopyrimidin-4-amine
InChIKey
YTKGAYFHUZTLCI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
EU Max Conc.
1.5%
US US Status
permitted
US Notes
No FDA monograph. Proprietary L'Oreal ingredient. SCCNFP evaluated and approved.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Aminexil.
Calculate MoS for your specific formulation with the MoS Calculator.
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: Hair products. Max: 0.015.
BRIN Brazil/India Cosmetics
Brazil: Restricted · max 1,5%
India: Restricted · max 0.015
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | restricted | 1.5% | Hair care products (anti-hair loss) |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Regulatory List Membership (1)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Aminexil.
Regulatory Flags
Restricted
eu_cosing_listed
Known Synonyms
6-Amino-2-iminopyrimidin-1(2H)-ol
2,4-Pyrimidinediamine, 3-oxide
2,4-Diaminopyrimidine 3-N-oxide
2,6-Diaminopyrimidin-1-ium-1-olate
Chemical Function
Softener and conditioner
Regulatory Lists
Europe; Personal care; restricted
Frequently Asked Questions
Is Aminexil allowed in the EU?
Aminexil EU regulatory status: restricted. Maximum allowed concentration: 1.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Aminexil do in cosmetics?
Aminexil functions as: Hair conditioning. It is classified as a Active Ingredient in our database. CAS number: 74638-76-9.
Is Aminexil used outside cosmetics?
Aminexil also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Aminexil compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Antioxidant
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Chemical family
Hair Conditioning, Skin Conditioning
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