Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Diheptyl Succinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 630 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 630 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Safe silicone replacement per CIR class assessment; COSMOS-approved, with data gaps in dermal absorption and sensitization.
Frequently Asked Questions
Is Diheptyl Succinate safe in cosmetics?
Safe silicone replacement per CIR class assessment; COSMOS-approved, with data gaps in dermal absorption and sensitization. The EU classifies Diheptyl Succinate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Diheptyl Succinate allowed in the EU?
Diheptyl Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diheptyl Succinate do in cosmetics?
Diheptyl Succinate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 15872-89-6.
What is the Margin of Safety for Diheptyl Succinate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diheptyl Succinate?
The NOAEL (No Observed Adverse Effect Level) for Diheptyl Succinate is 630 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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