Excellent Cosmetic Ingredient NOAEL Data

Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters

INCI: ACACIA DECURRENS/JOJOBA/SUNFLOWER SEED WAX POLYGLYCERYL-3 ESTERS

CAS Number
N/A
Function
Skin conditioning emollient, texturizer
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes All components TSCA-listed. CIR 2023 assessed 274 polyglyceryl fatty acid esters as safe when formulated to be non-irritating.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

7 study endpoints found for Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 30 mg/kg bw/day dermal - - SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day - - reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day oral rat reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day oral - reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day dermal - - SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day oral - reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day - - reproductive SCCS_PDF_extraction

Expert Verdict

Plant-derived wax ester blend assessed safe by CIR 2023 when formulated to be non-irritating; COSMOS-approved with natural origin index 1.0.

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Concern Level: None

Frequently Asked Questions

Is Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters safe in cosmetics?

Plant-derived wax ester blend assessed safe by CIR 2023 when formulated to be non-irritating; COSMOS-approved with natural origin index 1.0. The EU classifies Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters as "permitted". Safety rating: EXCELLENT. 7 toxicological study endpoint(s) are available in our database.

Is Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters allowed in the EU?

Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters do in cosmetics?

Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters functions as: Skin conditioning emollient, texturizer. It is classified as a cosmetic ingredient in our database. CAS number: N/A.

What is the Margin of Safety for Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters?

The NOAEL (No Observed Adverse Effect Level) for Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters is 30 mg/kg bw/day based on a toxicological study via dermal route in rat. A total of 7 study endpoints are available. Source: SCCS_PDF_extraction.

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