Excellent Cosmetic Ingredient NOAEL Data

Acetyl Triethylhexyl Citrate

INCI: ACETYL TRIETHYLHEXYL CITRATE

CAS Number
144-15-0
Function
Emollient, Film Forming, Plasticiser
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics. CIR-reviewed - Expert Panel concluded safe as used based on structural similarity data from the acetyl citrate ester group.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Acetyl Triethylhexyl Citrate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

None significant. CIR explicitly stated no restrictions necessary for rinse-off or leave-on products. EPA TSCA active substance.

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Concern Level: None

Frequently Asked Questions

Is Acetyl Triethylhexyl Citrate safe in cosmetics?

None significant. CIR explicitly stated no restrictions necessary for rinse-off or leave-on products. EPA TSCA active substance. The EU classifies Acetyl Triethylhexyl Citrate as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.

Is Acetyl Triethylhexyl Citrate allowed in the EU?

Acetyl Triethylhexyl Citrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetyl Triethylhexyl Citrate do in cosmetics?

Acetyl Triethylhexyl Citrate functions as: Emollient, Film Forming, Plasticiser. It is classified as a cosmetic ingredient in our database. CAS number: 144-15-0.

What is the Margin of Safety for Acetyl Triethylhexyl Citrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Acetyl Triethylhexyl Citrate?

The NOAEL (No Observed Adverse Effect Level) for Acetyl Triethylhexyl Citrate is >=1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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