Good Cosmetic Ingredient NOAEL Data

Dihydromyrcenyl Acetate

INCI: DIHYDROMYRCENYL ACETATE

CAS Number
53767-93-4
Function
Perfuming — sweet, spicy-herbaceous, fresh, fruity odor with bergamot-lime character
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted — no specific CFR cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Dihydromyrcenyl Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=868.7 mg/kg bw/day oral rat oral REACH
NOAEL >=868.7 mg/kg bw/day oral rat oral REACH

Expert Verdict

Confirmed sensitizer with IFRA concentration limits applied by product category (lip products ≤0.0025%, body lotion ≤0.24%); Cramer Class I; not genotoxic; not PBT; RfD = 0.50 mg/kg/day.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Dihydromyrcenyl Acetate safe in cosmetics?

Confirmed sensitizer with IFRA concentration limits applied by product category (lip products ≤0.0025%, body lotion ≤0.24%); Cramer Class I; not genotoxic; not PBT; RfD = 0.50 mg/kg/day. The EU classifies Dihydromyrcenyl Acetate as "restricted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Dihydromyrcenyl Acetate allowed in the EU?

Dihydromyrcenyl Acetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dihydromyrcenyl Acetate do in cosmetics?

Dihydromyrcenyl Acetate functions as: Perfuming — sweet, spicy-herbaceous, fresh, fruity odor with bergamot-lime character. It is classified as a cosmetic ingredient in our database. CAS number: 53767-93-4.

What is the Margin of Safety for Dihydromyrcenyl Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Dihydromyrcenyl Acetate?

The NOAEL (No Observed Adverse Effect Level) for Dihydromyrcenyl Acetate is >=868.7 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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