Regulatory Status
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Safety Data
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Expert Verdict
Diisocetyl Adipate is assessed safe by CIR (2012) via read-across from structurally related adipate esters, with very low acute toxicity and negligible expected dermal absorption due to extremely high lipophilicity (XLogP3 15.5) and large molecular weight (595 g/mol).
Regulatory Flags
Frequently Asked Questions
Is Diisocetyl Adipate safe in cosmetics?
Diisocetyl Adipate is assessed safe by CIR (2012) via read-across from structurally related adipate esters, with very low acute toxicity and negligible expected dermal absorption due to extremely high lipophilicity (XLogP3 15.5) and large molecular weight (595 g/mol). The EU classifies Diisocetyl Adipate as "permitted". Safety rating: GOOD.
Is Diisocetyl Adipate allowed in the EU?
Diisocetyl Adipate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisocetyl Adipate do in cosmetics?
Diisocetyl Adipate functions as: Plasticizer, Skin Conditioning, Emollient, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 59686-69-0.
What is the Margin of Safety for Diisocetyl Adipate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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