Dimethicone/Silsesquioxane Copolymer

INCI: DIMETHICONE/SILSESQUIOXANE COPOLYMER

CAS Number
Not individually assigned (related: vinyl dimethicone/methicone silsesquioxane crosspolymer CAS 243137-53-3 or 153668-87-2)
Function
Skin conditioning, anti-caking, viscosity controlling
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — Not included in CIR 2012 crosspolymer report (copolymer vs. crosspolymer distinction); related silsesquioxane crosspolymers were reviewed.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not directly CIR-reviewed as a copolymer; read-across data from related silsesquioxane crosspolymers show safety (HRIPT safe, non-irritating, non-sensitizing, Ames negative). If particulate form, confirm particle size >10 µm to avoid inhalation risk.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Dimethicone/Silsesquioxane Copolymer safe in cosmetics?

Not directly CIR-reviewed as a copolymer; read-across data from related silsesquioxane crosspolymers show safety (HRIPT safe, non-irritating, non-sensitizing, Ames negative). If particulate form, confirm particle size >10 µm to avoid inhalation risk. The EU classifies Dimethicone/Silsesquioxane Copolymer as "permitted". Safety rating: MODERATE.

Is Dimethicone/Silsesquioxane Copolymer allowed in the EU?

Dimethicone/Silsesquioxane Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethicone/Silsesquioxane Copolymer do in cosmetics?

Dimethicone/Silsesquioxane Copolymer functions as: Skin conditioning, anti-caking, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (related: vinyl dimethicone/methicone silsesquioxane crosspolymer CAS 243137-53-3 or 153668-87-2).

What is the Margin of Safety for Dimethicone/Silsesquioxane Copolymer?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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