Poor Cosmetic Ingredient NOAEL Data

Allyl Methacrylate

INCI: ALLYL METHACRYLATE

CAS Number
96-05-9
Function
Cross-linking monomer; used as a building block for polymers in cosmetics (film forming, viscosity controlling)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated by FDA for cosmetics; used industrially as a monomer

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

8 study endpoints found for Allyl Methacrylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 15 mg/kg bw/day oral rat oral REACH
NOAEL 25 mg/kg bw/day dermal code:3484 dermal REACH
NOAEL 8 mg/kg bw/day oral mouse oral REACH
NOAEL 6 mg/kg bw/day oral rat oral REACH
NOAEL >=124.1 mg/kg bw/day oral rat oral REACH
NOAEL 8 mg/kg bw/day oral mouse oral REACH
NOAEL 6 mg/kg bw/day oral rat oral REACH
NOAEL >=124.1 mg/kg bw/day oral rat oral REACH

Expert Verdict

Free monomer is a skin sensitizer and irritant; must only be present as part of a polymerized system with controlled residual monomer levels

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Allyl Methacrylate safe in cosmetics?

Free monomer is a skin sensitizer and irritant; must only be present as part of a polymerized system with controlled residual monomer levels The EU classifies Allyl Methacrylate as "restricted". Safety rating: POOR. 8 toxicological study endpoint(s) are available in our database.

Is Allyl Methacrylate allowed in the EU?

Allyl Methacrylate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Allyl Methacrylate do in cosmetics?

Allyl Methacrylate functions as: Cross-linking monomer; used as a building block for polymers in cosmetics (film forming, viscosity controlling). It is classified as a cosmetic ingredient in our database. CAS number: 96-05-9.

What is the Margin of Safety for Allyl Methacrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Allyl Methacrylate?

The NOAEL (No Observed Adverse Effect Level) for Allyl Methacrylate is 15 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.

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