Good Cosmetic Ingredient NOAEL Data

Dimethyl Phenylbutanol

INCI: DIMETHYL PHENYLBUTANOL

CAS Number
2035-93-0
Function
Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted as fragrance ingredient; self-regulated under IFRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Dimethyl Phenylbutanol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL ca.100 mg/kg bw/day oral rat oral REACH

Expert Verdict

Dimethyl Phenylbutanol is a permitted fragrance ingredient regulated under IFRA guidelines with a GOOD safety profile.

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Concern Level: Low

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Dimethyl Phenylbutanol safe in cosmetics?

Dimethyl Phenylbutanol is a permitted fragrance ingredient regulated under IFRA guidelines with a GOOD safety profile. The EU classifies Dimethyl Phenylbutanol as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Dimethyl Phenylbutanol allowed in the EU?

Dimethyl Phenylbutanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dimethyl Phenylbutanol do in cosmetics?

Dimethyl Phenylbutanol functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 2035-93-0.

What is the Margin of Safety for Dimethyl Phenylbutanol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Dimethyl Phenylbutanol?

The NOAEL (No Observed Adverse Effect Level) for Dimethyl Phenylbutanol is ca.100 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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