Isoamyl Octanoate

INCI: ISOAMYL OCTANOATE

CAS Number
2035-99-6 [^1_4]
Function
Skin conditioning agent — emollient; fragrance ingredient
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Not genotoxic (BlueScreen assay negative ± S9). Cramer Class I (low toxicity concern). PEC/PNEC <1 (environmentally safe).

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component jecfa_safe

Frequently Asked Questions

Is Isoamyl Octanoate safe in cosmetics?

Not genotoxic (BlueScreen assay negative ± S9). Cramer Class I (low toxicity concern). PEC/PNEC <1 (environmentally safe). The EU classifies Isoamyl Octanoate as "permitted". Safety rating: EXCELLENT.

Is Isoamyl Octanoate allowed in the EU?

Isoamyl Octanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoamyl Octanoate do in cosmetics?

Isoamyl Octanoate functions as: Skin conditioning agent — emollient; fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 2035-99-6 [^1_4].

What is the Margin of Safety for Isoamyl Octanoate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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