DIOXOLANE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for DIOXOLANE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 75 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 75 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
DIOXOLANE is listed in the EU CosIng database with functions: Solvent It is permitted in the EU without specific restrictions.
Regulatory Flags
Frequently Asked Questions
Is DIOXOLANE safe in cosmetics?
DIOXOLANE is listed in the EU CosIng database with functions: Solvent It is permitted in the EU without specific restrictions. The EU classifies DIOXOLANE as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is DIOXOLANE allowed in the EU?
DIOXOLANE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does DIOXOLANE do in cosmetics?
DIOXOLANE functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 646-06-0.
What is the NOAEL for DIOXOLANE?
The NOAEL (No Observed Adverse Effect Level) for DIOXOLANE is 75 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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