Dipeptide-5

INCI: DIPEPTIDE-5

CAS Number
Not uniquely confirmed for the base peptide; palmitoyl derivatives: 794590-34-4 (Palmitoyl Dipeptide-5 Diaminohydroxybutyrate), 883558-32-5 (Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine)
Function
Skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not specifically listed in 21 CFR as prohibited/restricted; subject to MoCRA reporting

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Palmitoyl derivatives have SDS data showing no GHS classification; acute toxicity data unavailable; no carcinogenicity flags per IARC/OSHA.

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Concern Level: Moderate

Frequently Asked Questions

Is Dipeptide-5 safe in cosmetics?

Palmitoyl derivatives have SDS data showing no GHS classification; acute toxicity data unavailable; no carcinogenicity flags per IARC/OSHA. The EU classifies Dipeptide-5 as "permitted". Safety rating: MODERATE.

Is Dipeptide-5 allowed in the EU?

Dipeptide-5 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dipeptide-5 do in cosmetics?

Dipeptide-5 functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely confirmed for the base peptide; palmitoyl derivatives: 794590-34-4 (Palmitoyl Dipeptide-5 Diaminohydroxybutyrate), 883558-32-5 (Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine).

What is the Margin of Safety for Dipeptide-5?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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