Dipeptide-7

INCI: DIPEPTIDE-7

CAS Number
Not publicly listed in available databases for the standalone (non-palmitoylated) form. Note: Palmitoyl Dipeptide-7 (a lipopeptide derivative) carries CAS 911813-90-6, but that is a separate INCI entry.
Function
Skin conditioning. The palmitoylated derivative promotes synthesis of type I collagen, type IV collagen, and fibronectin in dermal fibroblasts, and enhances epidermal differentiation.
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited or restricted. Falls under general cosmetic ingredient safety requirements (manufacturer responsibility under MoCRA).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No known significant safety issues. CIR reviewed palmitoyl oligopeptides (including palmitoyl dipeptide-7) and published a safety assessment.. One of the shortest peptides used in cosmetics; typically encountered as the palmitoyl conjugate for enhanced skin penetration and stability.

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Concern Level: Moderate

Frequently Asked Questions

Is Dipeptide-7 safe in cosmetics?

No known significant safety issues. CIR reviewed palmitoyl oligopeptides (including palmitoyl dipeptide-7) and published a safety assessment.. One of the shortest peptides used in cosmetics; typically encountered as the palmitoyl conjugate for enhanced skin penetration and stability. The EU classifies Dipeptide-7 as "permitted". Safety rating: MODERATE.

Is Dipeptide-7 allowed in the EU?

Dipeptide-7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dipeptide-7 do in cosmetics?

Dipeptide-7 functions as: Skin conditioning. The palmitoylated derivative promotes synthesis of type I collagen, type IV collagen, and fibronectin in dermal fibroblasts, and enhances epidermal differentiation.. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in available databases for the standalone (non-palmitoylated) form. Note: Palmitoyl Dipeptide-7 (a lipopeptide derivative) carries CAS 911813-90-6, but that is a separate INCI entry..

What is the Margin of Safety for Dipeptide-7?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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