Diethyl Glutamate

INCI: DIETHYL GLUTAMATE

CAS Number
55895-85-7 (DL-form) / 16450-41-2 (L-form)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Amino acid diethyl ester that hydrolyzes to glutamic acid (endogenous) and ethanol. No CIR monograph available; CIR assessed Tetrasodium Glutamate Diacetate (a different glutamate derivative) but data are not directly transferable. Supplier toxicological data needed.

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Concern Level: Moderate

Frequently Asked Questions

Is Diethyl Glutamate safe in cosmetics?

Amino acid diethyl ester that hydrolyzes to glutamic acid (endogenous) and ethanol. No CIR monograph available; CIR assessed Tetrasodium Glutamate Diacetate (a different glutamate derivative) but data are not directly transferable. Supplier toxicological data needed. The EU classifies Diethyl Glutamate as "permitted". Safety rating: MODERATE.

Is Diethyl Glutamate allowed in the EU?

Diethyl Glutamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diethyl Glutamate do in cosmetics?

Diethyl Glutamate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 55895-85-7 (DL-form) / 16450-41-2 (L-form).

What is the Margin of Safety for Diethyl Glutamate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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