Diphenylmethyl Piperazinylbenzimidazole

INCI: DIPHENYLMETHYL PIPERAZINYLBENZIMIDAZOLE

CAS Number
65215-54-5
Function
UV absorber
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not listed as an approved OTC sunscreen active in 21 CFR 352. Would require FDA monograph or NDA pathway for sunscreen claims.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major regulatory gap: not approved by FDA as sunscreen active and not assessed by SCCS. Piperazine moiety raises toxicological concerns including reproductive toxicity and sensitization potential. Not recommended for use without full safety dossier submission.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Diphenylmethyl Piperazinylbenzimidazole safe in cosmetics?

Major regulatory gap: not approved by FDA as sunscreen active and not assessed by SCCS. Piperazine moiety raises toxicological concerns including reproductive toxicity and sensitization potential. Not recommended for use without full safety dossier submission. The EU classifies Diphenylmethyl Piperazinylbenzimidazole as "permitted". Safety rating: POOR.

Is Diphenylmethyl Piperazinylbenzimidazole allowed in the EU?

Diphenylmethyl Piperazinylbenzimidazole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Diphenylmethyl Piperazinylbenzimidazole do in cosmetics?

Diphenylmethyl Piperazinylbenzimidazole functions as: UV absorber. It is classified as a cosmetic ingredient in our database. CAS number: 65215-54-5.

What is the Margin of Safety for Diphenylmethyl Piperazinylbenzimidazole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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