Moderate Cosmetic Ingredient NOAEL Data SCCS/CIR Reviewed

Disperse Violet 1

INCI: DISPERSE VIOLET 1

CAS Number
128-95-0
Function
Hair dyeing (anthraquinone dye); non-oxidative colouring agent
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
EU Max Conc. 0.5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed under 21 CFR 73/74/82; coal tar exemption applies with labeling

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Disperse Violet 1. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 0.25 mg/kg bw/day oral rat Subchronic COSMOS_DB
LOAEL 2 mg/kg bw/day oral rat Subchronic COSMOS_DB

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: unknown

Expert Verdict

Prohibited in EU due to insufficient safety data and sensitization risk from the active dye and Disperse Red 15 impurity; permitted in US under coal tar exemption with labeling requirements.

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Concern Level: High

Regulatory Flags

potential-allergen eu_cosing_listed

Frequently Asked Questions

Is Disperse Violet 1 safe in cosmetics?

Prohibited in EU due to insufficient safety data and sensitization risk from the active dye and Disperse Red 15 impurity; permitted in US under coal tar exemption with labeling requirements. The EU classifies Disperse Violet 1 as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is Disperse Violet 1 allowed in the EU?

Disperse Violet 1 EU regulatory status: prohibited. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Disperse Violet 1 do in cosmetics?

Disperse Violet 1 functions as: Hair dyeing (anthraquinone dye); non-oxidative colouring agent. It is classified as a cosmetic ingredient in our database. CAS number: 128-95-0.

What is the Margin of Safety for Disperse Violet 1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Disperse Violet 1?

The NOAEL (No Observed Adverse Effect Level) for Disperse Violet 1 is 0.25 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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