Also known as: C.I. Disperse Violet 9, 1,4-Anthraquinonyldiamine, Celliton Fast Red Violet R, Cibacet Violet E2R, Cibacete Violet 2R (+10 more)
INCI: DISPERSE VIOLET 1
Disperse Violet 1 (CAS 128-95-0) is a cosmetic cosmetic ingredient functioning as Hair dyeing (anthraquinone dye); non-oxidative colouring agent. Reported NOAEL =1.21 mg/kg in guinea pig (SCCNFP Opinion); EU Regulation 1223/2009 status: prohibited, max 0.5%; 1 safety opinion reviewed (CIR Safety Assessment). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
US NotesNot specifically listed under 21 CFR 73/74/82; coal tar exemption applies with labeling
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Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Disperse Violet 1.
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Toxicological Studies
10 study endpoints found for Disperse Violet 1. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=1.21 mg/kg
-
guinea pig
irritation
SCCNFP Opinion
NOAEL
=1.21 mg/kg/day
oral
rat
repeated dose toxicity
SCCNFP Opinion
NOAEL
=1.21 mg/kg
-
guinea pig
irritation
SCCNFP Opinion
NOAEL
=1.21 mg/kg/day
oral
rat
repeated dose toxicity
SCCNFP Opinion
NOAEL
=1.21 mg/kg
-
guinea pig
irritation
SCCNFP Opinion
NOAEL
=1.21 mg/kg/day
oral
rat
repeated dose toxicity
SCCNFP Opinion
NOAEL
=1.21 mg/kg
-
guinea pig
irritation
SCCNFP Opinion
NOAEL
=1.21 mg/kg/day
oral
rat
repeated dose toxicity
SCCNFP Opinion
NOAEL
=0.003 mg/kg bw
oral
rat
dermal absorption
SCCS Opinion
NOAEL
=0.003 mg/kg bw
oral
rat
dermal absorption
SCCS Opinion
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
CIR Safety Assessment
Verdict: unknown
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
Disperse Violet 1 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by CIR Safety Assessment.
Is Disperse Violet 1 allowed in the EU?
Disperse Violet 1 EU regulatory status: prohibited. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Disperse Violet 1 do in cosmetics?
Disperse Violet 1 functions as: Hair dyeing (anthraquinone dye); non-oxidative colouring agent. It is classified as a cosmetic ingredient in our database. CAS number: 128-95-0.
What is the NOAEL for Disperse Violet 1?
The NOAEL (No Observed Adverse Effect Level) for Disperse Violet 1 is =1.21 mg/kg based on a irritation study via oral route in guinea pig. A total of 10 study endpoints are available. Source: SCCNFP Opinion.
Is Disperse Violet 1 used outside cosmetics?
Disperse Violet 1 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Disperse Violet 1 have different safety status in cosmetics vs industrial chemicals?
Disperse Violet 1 is prohibited in EU cosmetics at max 0.5% but has active industrial GHS classifications (H301, H317, H373).
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