Dodecahydro-Tetramethylnaphthofuran (Ambroxan)

INCI: DODECAHYDRO-TETRAMETHYLNAPHTHOFURAN

CAS Number
6790-58-5
Function
Fragrance ingredient (amber/ambergris note)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no 21 CFR restriction; widely used in fine fragrance

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

IFRA concentration limits by product category apply; olfactory notes include amber, ambergris, woody, fresh โ€” potent at low concentrations; supply-chain verification for isomeric purity recommended

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Dodecahydro-Tetramethylnaphthofuran (Ambroxan) safe in cosmetics?

IFRA concentration limits by product category apply; olfactory notes include amber, ambergris, woody, fresh โ€” potent at low concentrations; supply-chain verification for isomeric purity recommended The EU classifies Dodecahydro-Tetramethylnaphthofuran (Ambroxan) as "permitted". Safety rating: GOOD.

Is Dodecahydro-Tetramethylnaphthofuran (Ambroxan) allowed in the EU?

Dodecahydro-Tetramethylnaphthofuran (Ambroxan) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Dodecahydro-Tetramethylnaphthofuran (Ambroxan) do in cosmetics?

Dodecahydro-Tetramethylnaphthofuran (Ambroxan) functions as: Fragrance ingredient (amber/ambergris note). It is classified as a cosmetic ingredient in our database. CAS number: 6790-58-5.

What is the Margin of Safety for Dodecahydro-Tetramethylnaphthofuran (Ambroxan)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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