Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Dodecene-1. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Linear alpha-olefin used in cosmetics as a masking agent, solvent, and viscosity modifier; EU CosIng listed with no restrictions; generally regarded as safe at cosmetic use levels.
Regulatory Flags
Frequently Asked Questions
Is Dodecene-1 safe in cosmetics?
Linear alpha-olefin used in cosmetics as a masking agent, solvent, and viscosity modifier; EU CosIng listed with no restrictions; generally regarded as safe at cosmetic use levels. The EU classifies Dodecene-1 as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is Dodecene-1 allowed in the EU?
Dodecene-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dodecene-1 do in cosmetics?
Dodecene-1 functions as: Masking, Solvent, Viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 112-41-4.
What is the Margin of Safety for Dodecene-1?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dodecene-1?
The NOAEL (No Observed Adverse Effect Level) for Dodecene-1 is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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