Esculin

INCI: ESCULIN

CAS Number
531-75-9
Function
Light Stabilizer, Tonic, Antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR assessment published; no FDA restrictions under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted with caution; belongs to coumarin class and requires CPSR safety assessment of structural relationship to restricted coumarins.

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Concern Level: Moderate

Regulatory Flags

coumarin-class-flag no-dermal-absorption-data no-sccs-opinion no-cir-monograph cpsr-data-gap eu_children_restricted

Frequently Asked Questions

Is Esculin safe in cosmetics?

Permitted with caution; belongs to coumarin class and requires CPSR safety assessment of structural relationship to restricted coumarins. The EU classifies Esculin as "permitted". Safety rating: MODERATE.

Is Esculin allowed in the EU?

Esculin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Esculin do in cosmetics?

Esculin functions as: Light Stabilizer, Tonic, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 531-75-9.

What is the Margin of Safety for Esculin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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