Ethoxyheptyl Bicyclooctanone (Koavone™)

INCI: ETHOXYHEPTYL BICYCLOOCTANONE

CAS Number
188764-45-4 (verify with supplier — IFF proprietary molecule)
Function
Fragrance ingredient (woody note)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted. Not restricted under 21 CFR.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No carcinogenicity flags (IARC/OSHA clear). No eye irritation (OECD 438). Environmental profile acceptable (bacterial EC50 = 910 mg/L). Relatively new molecule — long-term post-market surveillance data still accumulating.

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Ethoxyheptyl Bicyclooctanone (Koavone™) safe in cosmetics?

No carcinogenicity flags (IARC/OSHA clear). No eye irritation (OECD 438). Environmental profile acceptable (bacterial EC50 = 910 mg/L). Relatively new molecule — long-term post-market surveillance data still accumulating. The EU classifies Ethoxyheptyl Bicyclooctanone (Koavone™) as "permitted". Safety rating: GOOD.

Is Ethoxyheptyl Bicyclooctanone (Koavone™) allowed in the EU?

Ethoxyheptyl Bicyclooctanone (Koavone™) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethoxyheptyl Bicyclooctanone (Koavone™) do in cosmetics?

Ethoxyheptyl Bicyclooctanone (Koavone™) functions as: Fragrance ingredient (woody note). It is classified as a cosmetic ingredient in our database. CAS number: 188764-45-4 (verify with supplier — IFF proprietary molecule).

What is the Margin of Safety for Ethoxyheptyl Bicyclooctanone (Koavone™)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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