Good Cosmetic Ingredient NOAEL Data

Ethyl Phenethyl Acetal

INCI: ETHYL PHENETHYL ACETAL

CAS Number
2556-10-7
Function
Fragrance / Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR; FEMA/GRAS status available for food use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Ethyl Phenethyl Acetal. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=377 mg/kg bw/day oral rat oral REACH

Expert Verdict

Standard fragrance precautions apply; IFRA concentration limits must be observed; not phototoxic or photoallergenic

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Concern Level: Low

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is Ethyl Phenethyl Acetal safe in cosmetics?

Standard fragrance precautions apply; IFRA concentration limits must be observed; not phototoxic or photoallergenic The EU classifies Ethyl Phenethyl Acetal as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Ethyl Phenethyl Acetal allowed in the EU?

Ethyl Phenethyl Acetal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Phenethyl Acetal do in cosmetics?

Ethyl Phenethyl Acetal functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 2556-10-7.

What is the Margin of Safety for Ethyl Phenethyl Acetal?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ethyl Phenethyl Acetal?

The NOAEL (No Observed Adverse Effect Level) for Ethyl Phenethyl Acetal is >=377 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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