Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Ethyl Polysilicate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >50 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Predominantly used in industrial coatings; hydrolysis releases ethanol and colloidal silica with potential eye and skin irritant effects from unreacted silicate esters; limited cosmetic use history requires scrutiny of intended concentration and application type.
Frequently Asked Questions
Is Ethyl Polysilicate safe in cosmetics?
Predominantly used in industrial coatings; hydrolysis releases ethanol and colloidal silica with potential eye and skin irritant effects from unreacted silicate esters; limited cosmetic use history requires scrutiny of intended concentration and application type. The EU classifies Ethyl Polysilicate as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Ethyl Polysilicate allowed in the EU?
Ethyl Polysilicate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Polysilicate do in cosmetics?
Ethyl Polysilicate functions as: Film forming. It is classified as a cosmetic ingredient in our database. CAS number: 11099-06-2.
What is the Margin of Safety for Ethyl Polysilicate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethyl Polysilicate?
The NOAEL (No Observed Adverse Effect Level) for Ethyl Polysilicate is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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