Ethylhexyl Isononanoate

INCI: ETHYLHEXYL ISONONANOATE

CAS Number
71566-49-9
Function
Skin conditioning agent — emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Listed in FDA GSRS (UNII I6KB4GE3K4); VCRP reported across multiple categories. CIR: Safe as used in two group reviews.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR safe in two group reviews as a nonanoate ester and alkyl ester; highest permeation enhancer in its class — caution when pairing with absorption-sensitive actives.

⚠️
Concern Level: Low

Regulatory Flags

PENETRATION_ENHANCER

Frequently Asked Questions

Is Ethylhexyl Isononanoate safe in cosmetics?

CIR safe in two group reviews as a nonanoate ester and alkyl ester; highest permeation enhancer in its class — caution when pairing with absorption-sensitive actives. The EU classifies Ethylhexyl Isononanoate as "permitted". Safety rating: GOOD.

Is Ethylhexyl Isononanoate allowed in the EU?

Ethylhexyl Isononanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylhexyl Isononanoate do in cosmetics?

Ethylhexyl Isononanoate functions as: Skin conditioning agent — emollient. It is classified as a cosmetic ingredient in our database. CAS number: 71566-49-9.

What is the Margin of Safety for Ethylhexyl Isononanoate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Ethylhexyl Isononanoate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ethylhexyl Isononanoate in your formulation.