Galactonolactone

INCI: GALACTONOLACTONE

CAS Number
2782-07-2 (D-galactonolactone) / 1668-08-2 (L-form) / 15892-28-1 (δ-lactone)
Function
Humectant, skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not prohibited or restricted; structurally analogous Gluconolactone is GRAS (21 CFR 172.580)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR (2022) assessed glycolactones as a class; Galactonolactone had no reported cosmetic use and therefore no use-concentration data for MoS calculation; read-across from Gluconolactone may be defensible but requires formal justification in a CPSR

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Concern Level: Moderate

Frequently Asked Questions

Is Galactonolactone safe in cosmetics?

CIR (2022) assessed glycolactones as a class; Galactonolactone had no reported cosmetic use and therefore no use-concentration data for MoS calculation; read-across from Gluconolactone may be defensible but requires formal justification in a CPSR The EU classifies Galactonolactone as "permitted". Safety rating: MODERATE.

Is Galactonolactone allowed in the EU?

Galactonolactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Galactonolactone do in cosmetics?

Galactonolactone functions as: Humectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 2782-07-2 (D-galactonolactone) / 1668-08-2 (L-form) / 15892-28-1 (δ-lactone).

What is the Margin of Safety for Galactonolactone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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