Is gamma-Methyldecalactone safe in cosmetics?
gamma-Methyldecalactone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
gamma-Methyldecalactone
Also known as: gamma-Methyl-gamma-decanolactone, 2(3H)-Furanone, 5-hexyldihydro-5-methyl-, gamma-Methyl decalactone, BRN 0123344, EINECS 230-291-1 (+6 more)
INCI: GAMMA-METHYLDECALACTONE
gamma-Methyldecalactone (CAS 7011-83-8) is a cosmetic cosmetic ingredient functioning as Fragrance / flavoring agent (synonyms: dihydrojasmone lactone;. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Fragrance / flavoring agent (synonyms: dihydrojasmone lactone; 5-hexyldihydro-5-methylfuran-2(3H)-one)
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
5-hexyl-5-methyloxolan-2-one
InChIKey
ALWUKGXLBSQSMA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA 3786; FDA listed in Substances Added to Food
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for gamma-Methyldecalactone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1350 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
250
Source: WHO/JECFA
JECFA Evaluation
gamma-METHYLDECALACTONE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/42 | FAS 40-JECFA 49/231
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for gamma-Methyldecalactone — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
gamma-Methyl-gamma-decanolactone
2(3H)-Furanone, 5-hexyldihydro-5-methyl-
gamma-Methyl decalactone
BRN 0123344
EINECS 230-291-1
FEMA No. 3786
5-Hexyldihydro-5-methyl-2(3H)-furanone
4-Hydroxy-4-methyldecanoic acid gamma-lactone
4-Methyldecanolide
NSC 141822
UNII-ANJ13KO1RK
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182347
Frequently Asked Questions
Is gamma-Methyldecalactone allowed in the EU?
gamma-Methyldecalactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does gamma-Methyldecalactone do in cosmetics?
gamma-Methyldecalactone functions as: Fragrance / flavoring agent (synonyms: dihydrojasmone lactone; 5-hexyldihydro-5-methylfuran-2(3H)-one). It is classified as a cosmetic ingredient in our database. CAS number: 7011-83-8.
Is gamma-Methyldecalactone used outside cosmetics?
gamma-Methyldecalactone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check gamma-Methyldecalactone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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