Gentiana Lutea Extract

INCI: GENTIANA LUTEA EXTRACT

CAS Number
Not specifically assigned (related root-extract CAS: 72968-42-4)
Function
Skin conditioning, emollient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR; GRAS for flavor use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited non-clinical safety data per EMA/HMPC; no reproductive toxicity or carcinogenicity studies available; cross-reactivity risk with Veratrum album if botanical identification is poor.

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Gentiana Lutea Extract safe in cosmetics?

Limited non-clinical safety data per EMA/HMPC; no reproductive toxicity or carcinogenicity studies available; cross-reactivity risk with Veratrum album if botanical identification is poor. The EU classifies Gentiana Lutea Extract as "permitted". Safety rating: GOOD.

Is Gentiana Lutea Extract allowed in the EU?

Gentiana Lutea Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gentiana Lutea Extract do in cosmetics?

Gentiana Lutea Extract functions as: Skin conditioning, emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (related root-extract CAS: 72968-42-4).

What is the Margin of Safety for Gentiana Lutea Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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