Gentiana Lutea Rhizome/Root

INCI: GENTIANA LUTEA RHIZOME/ROOT

CAS Number
97676-22-7
Function
Skin conditioning (raw herbal substance, typically powdered)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains 2โ€“8% bitter secoiridoid glycosides (gentiopicroside, amarogentin) and up to 1% xanthones; xanthones may exhibit phototoxic potential at high concentrations; no genotoxicity concern flagged in EMA review

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Concern Level: Moderate

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Gentiana Lutea Rhizome/Root safe in cosmetics?

Contains 2โ€“8% bitter secoiridoid glycosides (gentiopicroside, amarogentin) and up to 1% xanthones; xanthones may exhibit phototoxic potential at high concentrations; no genotoxicity concern flagged in EMA review The EU classifies Gentiana Lutea Rhizome/Root as "permitted". Safety rating: GOOD.

Is Gentiana Lutea Rhizome/Root allowed in the EU?

Gentiana Lutea Rhizome/Root EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gentiana Lutea Rhizome/Root do in cosmetics?

Gentiana Lutea Rhizome/Root functions as: Skin conditioning (raw herbal substance, typically powdered). It is classified as a cosmetic ingredient in our database. CAS number: 97676-22-7.

What is the Margin of Safety for Gentiana Lutea Rhizome/Root?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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