Good Cosmetic Ingredient NOAEL Data

Ghatti Gum

INCI: GHATTI GUM

CAS Number
9000-28-6
Function
Emulsifier, Viscosity Controlling, Film Forming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” also GRAS as food additive (21 CFR 184.1333); not restricted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Ghatti Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1700 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 1700 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 1700 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 150 mg/kg bw/day oral rabbit Developmental COSMOS_DB
dose_tested 1700 mg/kg bw/day oral mouse Developmental COSMOS_DB
dose_tested 1700 mg/kg bw/day oral hamster Developmental COSMOS_DB

Expert Verdict

Ghatti Gum is a permitted emulsifier and viscosity controlling agent with good safety profile and established margin of safety.

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Concern Level: Low

Regulatory Flags

fda_food_additive jecfa_concern

Frequently Asked Questions

Is Ghatti Gum safe in cosmetics?

Ghatti Gum is a permitted emulsifier and viscosity controlling agent with good safety profile and established margin of safety. The EU classifies Ghatti Gum as "permitted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.

Is Ghatti Gum allowed in the EU?

Ghatti Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ghatti Gum do in cosmetics?

Ghatti Gum functions as: Emulsifier, Viscosity Controlling, Film Forming. It is classified as a cosmetic ingredient in our database. CAS number: 9000-28-6.

What is the Margin of Safety for Ghatti Gum?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ghatti Gum?

The NOAEL (No Observed Adverse Effect Level) for Ghatti Gum is 1700 mg/kg bw/day based on a Developmental study via oral route in mouse. A total of 6 study endpoints are available. Source: COSMOS_DB.

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