Good Cosmetic Ingredient NOAEL Data

Acacia Senegal Gum

CAS Number
9000-01-5
Function
Adhesion/cohesion promoter; Deodorizer; Emulsifier; Film former; Flavouring and nutrient; Fragrance; Other; Processing aids not otherwise specified; Propellants, non-motive (blowing agents); Solvent; Stabilizing agent; Surfactant (surface active agent); Thickening agent; Viscosity modifier
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: S - IJT 24(Suppl. 3):75-118, 2005

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Acacia Senegal Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1600 mg/kg bw/day oral mouse Developmental COSMOS_DB
NOAEL 1600 mg/kg bw/day oral rat Developmental COSMOS_DB
NOAEL 1600 mg/kg bw/day oral hamster Developmental COSMOS_DB
NOAEL 800 mg/kg bw/day oral rabbit Developmental COSMOS_DB
NOAEL 30000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Subchronic COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB

Expert Verdict

Good safety profile with no skin penetration; generally recognized as safe for cosmetic use.

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Concern Level: Low

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Acacia Senegal Gum safe in cosmetics?

Good safety profile with no skin penetration; generally recognized as safe for cosmetic use. The EU classifies Acacia Senegal Gum as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Acacia Senegal Gum allowed in the EU?

Acacia Senegal Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acacia Senegal Gum do in cosmetics?

Acacia Senegal Gum functions as: Adhesion/cohesion promoter; Deodorizer; Emulsifier; Film former; Flavouring and nutrient; Fragrance; Other; Processing aids not otherwise specified; Propellants, non-motive (blowing agents); Solvent; Stabilizing agent; Surfactant (surface active agent); Thickening agent; Viscosity modifier. It is classified as a Cosmetic Ingredient in our database. CAS number: 9000-01-5.

What is the Margin of Safety for Acacia Senegal Gum?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Acacia Senegal Gum?

The NOAEL (No Observed Adverse Effect Level) for Acacia Senegal Gum is 1600 mg/kg bw/day based on a Developmental study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.

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