Good Cosmetic Ingredient NOAEL Data

Acacia Senegal Gum

Also known as: Acacia senegal, EINECS 232-519-5, FEMA No. 2001, Gum arabic (Acacia senegal (L.) Willd.), Gum arabicum (+6 more)

Acacia Senegal Gum (CAS 9000-01-5) is a cosmetic cosmetic ingredient functioning as Adhesion/cohesion promoter; Deodorizer; Emulsifier; Film former; Flavouring and. Reported NOAEL =2500 mg/kg bw/day in Rat (EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 9000-01-5 →

Auto-generated CPSR Part A draft with source citations
Function
Adhesion/cohesion promoter; Deodorizer; Emulsifier; Film former; Flavouring and nutrient; Fragrance; Other; Processing aids not otherwise specified; Propellants, non-motive (blowing agents); Solvent; Stabilizing agent; Surfactant (surface active agent); Thickening agent; Viscosity modifier
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR: S - IJT 24(Suppl. 3):75-118, 2005

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Acacia Senegal Gum.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Acacia Senegal Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =2500 mg/kg bw/day - Rat chronic/long term toxicity EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

EPA ToxValDB — Toxicity Values

6 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LEL =5220 mg/kg-day Rat oral subchronic EFSA
LEL =20000 mg/kg-day Mouse oral - EFSA
LEL =2500 mg/kg-day Rat oral chronic EFSA
LEL =7500 mg/kg-day Mouse oral chronic EFSA
LEL =760 mg/kg-day Human oral short-term EFSA
LD50 >16000 mg/kg Rat oral - TEST

Additional Ingredient Properties

6 property records from structured ingredient metadata.

biopolymer
{"cas_number": "9000-01-5", "polymer_class": "plant_gum", "botanical_source": "Acacia senegal/Acacia seyal", "molecular_weight_range_kDa": "250-1000", "monosaccharide_composition": "galactose/arabinose/rhamnose/glucuronic acid", "degree_of_branching": "highly_branched", "charge_type": "anionic", "viscosity_1pct_solution_mPas": "5-15", "pseudoplastic_behavior": "Newtonian", "thixotropy": "no", "yie…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,oily,combination,normal", "acne_safe": "yes", "source": "Natural gum"}
emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "emulsion_stabilization_mechanism": "steric_electrostatic", "co_emulsifier_pairs": "xanthan_gum", "optimal_oil_phase_pct": "5-25", "optimal_water_phase_pct": "75-95", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "4.0-8.5", "viscosity_building_contribution": "moderate", "droplet_size_range_um": "0.5-18", "zeta_po…
hair_care
{"hair_function": "styling", "hair_type_suitability": "all", "curl_pattern_suitability": "curly/coily", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "k…
sensory
{"silky": "gel-like", "smooth, glides easily": "smooth, gel", "dry-touch, non-greasy": "soft, smooth", "instant": "moderate", "low": "high", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.48", "transparent": "transparent", "colorless": "pale-yellow", "excellent": "fair", "light": "light", "synthetic": "botanical"}
solubility_hlb
{"water_soluble": "yes", "oil_soluble": "no", "soluble_in": "water, glycerin", "insoluble_in": "oils, ethanol, silicones, propylene glycol", "log_p": "-5.8", "melting_point_c": "240", "appearance": "white to yellow powder", "source": "Nexira"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adhesion/cohesion promoter Deodorizer Emulsifier Film former Flavouring and nutrient Fragrance Other Processing aids not otherwise specified Propellants non-motive (blowing agents)
Regulatory List Membership (4)
EU Regulated in Personal Care IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Acacia Senegal Gum.

Regulatory Flags

epa_safer_alternative ifra_fragrance fda_food_additive

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Acacia Senegal Gum by CAS number or substance name.

Studies
1
Lowest NOAEL
2500 mg/kg bw/day
Highest NOAEL
2500 mg/kg bw/day
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Known Synonyms

Acacia senegal EINECS 232-519-5 FEMA No. 2001 Gum arabic (Acacia senegal (L.) Willd.) Gum arabicum Gum Dragon NCI-C50748 Starsol No. 1 UNII-5C5403N26O Acacia senegal resin Acacia verek resin

Chemical Function

Film former Deodorizer Adhesion/cohesion promoter Fragrance Stabilizing agent

Regulatory Lists

Europe; Personal care IFRA Transparency food_additive; Substances Added to Food (formerly EAFUS) (2/2019) inert_ingredient; Pesticides inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides SCIL (9/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
1
View full pharmaceutical profile →

Frequently Asked Questions

Is Acacia Senegal Gum safe in cosmetics?

Acacia Senegal Gum has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Acacia Senegal Gum allowed in the EU?

Acacia Senegal Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acacia Senegal Gum do in cosmetics?

Acacia Senegal Gum functions as: Adhesion/cohesion promoter; Deodorizer; Emulsifier; Film former; Flavouring and nutrient; Fragrance; Other; Processing aids not otherwise specified; Propellants, non-motive (blowing agents); Solvent; Stabilizing agent; Surfactant (surface active agent); Thickening agent; Viscosity modifier. It is classified as a cosmetic ingredient in our database. CAS number: 9000-01-5.

What is the NOAEL for Acacia Senegal Gum?

The NOAEL (No Observed Adverse Effect Level) for Acacia Senegal Gum is =2500 mg/kg bw/day based on a chronic/long term toxicity study via oral route in Rat. Source: EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx.

Is Acacia Senegal Gum used outside cosmetics?

Acacia Senegal Gum also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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