Ginsenoside Rh1

INCI: GINSENOSIDE RH1

CAS Number
63223-86-9
Function
Skin conditioning, anti-inflammatory metabolite of saponin Re; reduces oxazolone-induced dermatitis in mice
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR concluded parent ingredients safe as used; not prohibited under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ginsenoside Rh1 is a saponin metabolite present at approximately 4.7% in red ginseng extract with low absorption and sensitization, though oral toxicity warnings and limited phototoxicity data warrant moderate concern.

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Concern Level: Moderate

Frequently Asked Questions

Is Ginsenoside Rh1 safe in cosmetics?

Ginsenoside Rh1 is a saponin metabolite present at approximately 4.7% in red ginseng extract with low absorption and sensitization, though oral toxicity warnings and limited phototoxicity data warrant moderate concern. The EU classifies Ginsenoside Rh1 as "permitted". Safety rating: GOOD.

Is Ginsenoside Rh1 allowed in the EU?

Ginsenoside Rh1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginsenoside Rh1 do in cosmetics?

Ginsenoside Rh1 functions as: Skin conditioning, anti-inflammatory metabolite of saponin Re; reduces oxazolone-induced dermatitis in mice. It is classified as a cosmetic ingredient in our database. CAS number: 63223-86-9.

What is the Margin of Safety for Ginsenoside Rh1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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