Glucuronolactone

INCI: GLUCURONOLACTONE

CAS Number
32449-92-6
Function
Humectant, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” GRAS as dietary supplement; not restricted in cosmetics under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Distinct from gluconolactone โ€” independent toxicity data set is limited, but endogenous biochemistry supports low concern.

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Concern Level: Low

Frequently Asked Questions

Is Glucuronolactone safe in cosmetics?

Distinct from gluconolactone โ€” independent toxicity data set is limited, but endogenous biochemistry supports low concern. The EU classifies Glucuronolactone as "permitted". Safety rating: GOOD.

Is Glucuronolactone allowed in the EU?

Glucuronolactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glucuronolactone do in cosmetics?

Glucuronolactone functions as: Humectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 32449-92-6.

What is the Margin of Safety for Glucuronolactone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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