Good Cosmetic Ingredient NOAEL Data

Glyceryl Hydrogenated Rosinate

INCI: GLYCERYL HYDROGENATED ROSINATE

CAS Number
65997-13-9
Function
Film former; skin conditioning agent — emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not restricted under 21 CFR; FDA-compliant; CIR: safe in present practices of use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Glyceryl Hydrogenated Rosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 3000 ppm oral rat oral REACH
NOEL 3000 ppm oral - oral REACH
NOAEL 18000 other oral rat oral REACH
NOAEL 18000 other oral - oral REACH
NOEL 500 other oral rat oral REACH
NOEL 500 other oral - oral REACH
NOEL 500 other oral rat oral REACH
NOEL 500 other oral - oral REACH
NOEL 10000 ppm oral rat oral REACH
NOAEL 1 other oral rat oral REACH

Expert Verdict

Residual rosin may cause allergic contact dermatitis in colophony-sensitive individuals; may cause minor skin irritation on abraded skin; respiratory irritation from processing fumes

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Glyceryl Hydrogenated Rosinate safe in cosmetics?

Residual rosin may cause allergic contact dermatitis in colophony-sensitive individuals; may cause minor skin irritation on abraded skin; respiratory irritation from processing fumes The EU classifies Glyceryl Hydrogenated Rosinate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Glyceryl Hydrogenated Rosinate allowed in the EU?

Glyceryl Hydrogenated Rosinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Hydrogenated Rosinate do in cosmetics?

Glyceryl Hydrogenated Rosinate functions as: Film former; skin conditioning agent — emollient. It is classified as a cosmetic ingredient in our database. CAS number: 65997-13-9.

What is the Margin of Safety for Glyceryl Hydrogenated Rosinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Glyceryl Hydrogenated Rosinate?

The NOAEL (No Observed Adverse Effect Level) for Glyceryl Hydrogenated Rosinate is 3000 ppm based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

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