Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Glyceryl Hydroxystearate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 5725 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 10 other | oral | rat | oral | REACH |
| NOAEL | 5725 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 10 other | oral | rat | oral | REACH |
| LOAEL | 10 other | oral | rat | oral | REACH |
| NOAEL | >5000 mg/kg bw/day | oral | - | oral | REACH |
| LOAEL | 10 other | oral | rat | oral | REACH |
| NOAEL | >5000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
CIR-assessed safe at class level; no EU or US restrictions; safety relies on read-across from glyceryl monoester group
Regulatory Flags
Frequently Asked Questions
Is Glyceryl Hydroxystearate safe in cosmetics?
CIR-assessed safe at class level; no EU or US restrictions; safety relies on read-across from glyceryl monoester group The EU classifies Glyceryl Hydroxystearate as "permitted". Safety rating: GOOD. 8 toxicological study endpoint(s) are available in our database.
Is Glyceryl Hydroxystearate allowed in the EU?
Glyceryl Hydroxystearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glyceryl Hydroxystearate do in cosmetics?
Glyceryl Hydroxystearate functions as: Skin Conditioning — Emollient; Surfactant — Emulsifying Agent. It is classified as a cosmetic ingredient in our database. CAS number: 1323-42-8.
What is the Margin of Safety for Glyceryl Hydroxystearate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Glyceryl Hydroxystearate?
The NOAEL (No Observed Adverse Effect Level) for Glyceryl Hydroxystearate is 5725 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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