Glyceryl Linolenate

Also known as: 9,12,15-Octadecatrienoic acid, 2,3-dihydroxypropyl ester, (9Z,12Z,15Z)-, (9Z,12Z,15Z)-2,3-Dihydroxypropyl octadecatrienoate, 1-Linolenoylglycerol, 3-O-(9Z,12Z,15Z-Octadecatrienoyl)glycerol, 9,12,15-Octadecatrienoic acid, 2,3-dihydroxypropyl ester, (Z,Z,Z)- (+3 more)

INCI: GLYCERYL LINOLENATE

Glyceryl Linolenate (CAS 18465-99-1) is a cosmetic cosmetic ingredient functioning as Skin Conditioning — Emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 18465-99-1 →

Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning — Emollient
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C21H36O4
MW
352.5 g/mol
PubChem CID
5367328
IUPAC Name
2,3-dihydroxypropyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
InChIKey
GGJRAQULURVTAJ-PDBXOOCHSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR concluded safe in present practices of use and concentration (2004, reaffirmed 2020); 2025 re-review ongoing

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Glyceryl Linolenate.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

1 property record from structured ingredient metadata.

emulsifier
{"cas_number": "18465-99-1", "ingredient_class": "W/O_emulsifier,co_emulsifier", "chemical_type": "glyceryl_ester", "HLB_value": "3.8", "HLB_required_for_oil_phase": "2-6", "emulsion_type_primary": "W/O", "droplet_size_typical_um": "5-10", "surface_tension_reduction_mN_m": "20-22", "interfacial_tension_reduction": "20-25", "foam_formation": "low", "liquid_crystal_formation": "low", "lamellar_phase…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Glyceryl Linolenate.

Regulatory Flags

emollient omega-3 cir-assessed cosmos-compatible oxidation-prone no-sccs-opinion 2025-re-review-ongoing

Known Synonyms

9,12,15-Octadecatrienoic acid, 2,3-dihydroxypropyl ester, (9Z,12Z,15Z)- (9Z,12Z,15Z)-2,3-Dihydroxypropyl octadecatrienoate 1-Linolenoylglycerol 3-O-(9Z,12Z,15Z-Octadecatrienoyl)glycerol 9,12,15-Octadecatrienoic acid, 2,3-dihydroxypropyl ester, (Z,Z,Z)- Linolenin, 1-mono- α-Glyceryl linolenate EINECS No.: 242-347-2

Chemical Function

Softener and conditioner

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL255922
View full pharmaceutical profile →

Frequently Asked Questions

Is Glyceryl Linolenate safe in cosmetics?

Glyceryl Linolenate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Glyceryl Linolenate allowed in the EU?

Glyceryl Linolenate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Linolenate do in cosmetics?

Glyceryl Linolenate functions as: Skin Conditioning — Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 18465-99-1.

Is Glyceryl Linolenate used outside cosmetics?

Glyceryl Linolenate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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