Gymnanthemum Amygdalinum Leaf

INCI: GYMNANTHEMUM AMYGDALINUM LEAF

CAS Number
Not specifically assigned
Function
Humectant, skin conditioning, skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed in 21 CFR prohibited/restricted lists

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Vernonia amygdalina (bitter leaf) contains vernonioside, sesquiterpene lactones, and steroid glycosides with documented pharmacological activity; Asteraceae allergy cross-reactivity risk; no CIR or SCCS review; requires full toxicology data from supplier.

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Concern Level: Moderate

Frequently Asked Questions

Is Gymnanthemum Amygdalinum Leaf safe in cosmetics?

Vernonia amygdalina (bitter leaf) contains vernonioside, sesquiterpene lactones, and steroid glycosides with documented pharmacological activity; Asteraceae allergy cross-reactivity risk; no CIR or SCCS review; requires full toxicology data from supplier. The EU classifies Gymnanthemum Amygdalinum Leaf as "permitted". Safety rating: MODERATE.

Is Gymnanthemum Amygdalinum Leaf allowed in the EU?

Gymnanthemum Amygdalinum Leaf EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Gymnanthemum Amygdalinum Leaf do in cosmetics?

Gymnanthemum Amygdalinum Leaf functions as: Humectant, skin conditioning, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned.

What is the Margin of Safety for Gymnanthemum Amygdalinum Leaf?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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