Moderate Cosmetic Ingredient NOAEL Data

HC Violet No. 1

INCI: HC VIOLET NO. 1

CAS Number
82576-75-8
Function
Hair dyeing (non-oxidative/semi-permanent)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted under coal tar hair dye exemption (FD&C Act §601(a))

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for HC Violet No. 1. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 50 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Nitroaniline derivative with nitrosation potential concerns similar to HC Red No. 3; prohibited in EU but permitted in US under coal tar hair dye exemption.

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Concern Level: High

Regulatory Flags

eu_cosing_listed

Frequently Asked Questions

Is HC Violet No. 1 safe in cosmetics?

Nitroaniline derivative with nitrosation potential concerns similar to HC Red No. 3; prohibited in EU but permitted in US under coal tar hair dye exemption. The EU classifies HC Violet No. 1 as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is HC Violet No. 1 allowed in the EU?

HC Violet No. 1 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does HC Violet No. 1 do in cosmetics?

HC Violet No. 1 functions as: Hair dyeing (non-oxidative/semi-permanent). It is classified as a cosmetic ingredient in our database. CAS number: 82576-75-8.

What is the Margin of Safety for HC Violet No. 1?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for HC Violet No. 1?

The NOAEL (No Observed Adverse Effect Level) for HC Violet No. 1 is 50 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

Compliance Tools

Check HC Violet No. 1 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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