Moderate Cosmetic Ingredient Sensitization Data

Helianthus Annuus Extract

INCI: HELIANTHUS ANNUUS EXTRACT

CAS Number
84776-03-4
Function
Skin-conditioning agent – miscellaneous
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted – not prohibited/restricted; VCRP: 96 formulations reported

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Helianthus Annuus Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; ESSCA; NACDG

Expert Verdict

CIR Panel concluded insufficient data for this whole-plant extract; Asteraceae cross-reactivity risk in atopic populations; contains sesquiterpene lactones; formulators must verify constituent levels.

⚠️
Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Helianthus Annuus Extract safe in cosmetics?

CIR Panel concluded insufficient data for this whole-plant extract; Asteraceae cross-reactivity risk in atopic populations; contains sesquiterpene lactones; formulators must verify constituent levels. The EU classifies Helianthus Annuus Extract as "permitted". Safety rating: MODERATE.

Is Helianthus Annuus Extract allowed in the EU?

Helianthus Annuus Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Helianthus Annuus Extract do in cosmetics?

Helianthus Annuus Extract functions as: Skin-conditioning agent – miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: 84776-03-4.

What is the Margin of Safety for Helianthus Annuus Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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