Good Cosmetic Ingredient Sensitization Data

Helichrysum Italicum Extract

INCI: HELICHRYSUM ITALICUM EXTRACT

CAS Number
90045-56-0 / EINECS 289-918-2
Function
Skin conditioning, perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited under 21 CFR; FEMA 2592 (GRAS for flavor)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Helichrysum Italicum Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; literature review

Expert Verdict

Broad INCI covering whole plant extracts with variable composition; request full specification from supplier including solvent, concentration, and standardization; may contain Annex III declarable allergens (linalool, limonene, geraniol) at trace levels depending on process.

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Concern Level: Moderate

Regulatory Flags

plant-extract potential-allergen fragrance-component natural-origin

Frequently Asked Questions

Is Helichrysum Italicum Extract safe in cosmetics?

Broad INCI covering whole plant extracts with variable composition; request full specification from supplier including solvent, concentration, and standardization; may contain Annex III declarable allergens (linalool, limonene, geraniol) at trace levels depending on process. The EU classifies Helichrysum Italicum Extract as "permitted". Safety rating: GOOD.

Is Helichrysum Italicum Extract allowed in the EU?

Helichrysum Italicum Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Helichrysum Italicum Extract do in cosmetics?

Helichrysum Italicum Extract functions as: Skin conditioning, perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 90045-56-0 / EINECS 289-918-2.

What is the Margin of Safety for Helichrysum Italicum Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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