Heptapeptide-5

INCI: HEPTAPEPTIDE-5

CAS Number
Not assigned (Palmitoyl Heptapeptide-5 also listed with no CAS)
Function
Skin conditioning, anti-wrinkle
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted, not specifically restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Palmitoylated derivative has CIR support; unmodified Heptapeptide-5 has more limited direct data but used at concentrations typically โ‰ค0.005% in commercial products.

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Concern Level: Low

Frequently Asked Questions

Is Heptapeptide-5 safe in cosmetics?

Palmitoylated derivative has CIR support; unmodified Heptapeptide-5 has more limited direct data but used at concentrations typically โ‰ค0.005% in commercial products. The EU classifies Heptapeptide-5 as "permitted". Safety rating: GOOD.

Is Heptapeptide-5 allowed in the EU?

Heptapeptide-5 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Heptapeptide-5 do in cosmetics?

Heptapeptide-5 functions as: Skin conditioning, anti-wrinkle. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (Palmitoyl Heptapeptide-5 also listed with no CAS).

What is the Margin of Safety for Heptapeptide-5?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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